Third-Space Endoscopy

Pioneering Techniques for Advanced Gastrointestinal Care

What is Third-Space Endoscopy?

Third-space endoscopy is a groundbreaking, minimally invasive endoscopic technique that allows for therapeutic interventions in the submucosal space of the gastrointestinal (GI) tract. This innovative approach has revolutionized the treatment of complex GI conditions, offering a safe and effective alternative to traditional surgery.

At Central Gastro, we are proud to provide advanced third-space endoscopy procedures to treat a variety of conditions with precision and minimal discomfort.

Why is Third-Space Endoscopy Performed? 

Third-space endoscopy enables the treatment of complex gastrointestinal conditions that were previously managed with invasive surgeries. Common applications include:

1. Peroral Endoscopic Myotomy (POEM): 

• Treats achalasia and other esophageal motility disorders by cutting the muscle layers of the esophagus to improve swallowing. G-POEM treats similar stomach disorders.

2. Endoscopic Submucosal Tunneling:

• Used to access and treat lesions or tumors located deep in the GI wall.

3. Gastrointestinal Perforation Repair:

• Closes perforations or leaks in the esophagus, stomach, or intestines.

4. Zenker’s Diverticulotomy:

• Treats Zenker’s diverticulum by removing or reducing the pouch in the esophagus.

5. Resection of Submucosal Tumors (SMTs):

• Safely removes benign or malignant tumors located within the wall of the GI tract.

Conditions Treated with Third-Space Endoscopy

Third-space endoscopy is ideal for managing complex GI conditions, including:

• Achalasia and other esophageal motility disorders
• Zenker’s Diverticulum
• Submucosal tumors (SMTs) in the esophagus, stomach, or intestines
• Gastroparesis (delayed stomach emptying)
• Gastrointestinal perforations or leaks
• Complex strictures requiring advanced repair

How is Third-Space Endoscopy Performed?

Third-space endoscopy is performed using a flexible endoscope equipped with specialized tools, under sedation or general anesthesia for your comfort.

Steps of the Procedure:

1. Preparation:
   • Fasting for 6–8 hours before the procedure.
   • Sedation or anesthesia is administered to ensure patient comfort.
2. Procedure:
   • The endoscope is inserted through the mouth to access the GI tract.
   • A submucosal tunnel is created by lifting the mucosal layer to access the targeted area.
   • Therapeutic interventions such as cutting, repairing, or removing tissue are performed in the submucosal space.
   • The mucosal layer is closed after the procedure to promote healing.
3. Recovery:
   • The procedure typically takes 1–2 hours, depending on complexity.
   • Most patients can return home the same day or after an overnight observation.

Benefits of Third-Space Endoscopy

• Minimally Invasive: Avoids traditional open or laparoscopic surgeries.
• Precise Treatment: Targets the exact area of concern without affecting surrounding tissue.
• Faster Recovery: Reduced downtime and quicker return to normal activities.
• Lower Complication Risk: Minimizes the risks associated with conventional surgery.
• Comprehensive Approach: Combines diagnosis and treatment in a single session.

What to Expect After the Procedure

• Dietary Guidelines: You may need to follow a liquid or soft diet for a few days.
• Temporary Symptoms: Mild throat soreness or bloating may occur but typically resolves quickly.
• Follow-Up Care: Regular check-ups and imaging, if necessary, to ensure successful healing.